Opponents said the animals could hurt the ecosystem.
Pennsylvania legislators considered a plan to allow hedgehogs and sugar gliders to be kept as pets, but ultimately voted down the idea.
Pennsylvania's House of Representatives shot down the measure 120-71, Lancaster Online reports.
Opponents say such animals could harm the local ecosystem if they escaped, since they are non-native species.
Rep. David Zimmerman, who proposed the measure, said there's little chance of that, since the animals can't readily live in the wild in the Keystone State.
Kristen Tullo, Pennsylvania director for the Humane Society of the United States, praised the vote.
Lancaster Online quoted her saying: "Once the novelty wears off, owners often abandon exotic pets at shelters, turn them loose where they will either perish or threaten native ecosystems, or lock them away in a cage where they suffer from neglect."
The news outlets said four states prohibit the animals.
Read more at Lancaster Online